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. 2021 Sep 20;30(2):915–931. doi: 10.1016/j.ymthe.2021.09.017

Figure 6.

Figure 6

Knockdown of IRF4 circCdyl abolishes circCdyl knockdown induced M2 polarization

(A and C) Flow cytometry plots and quantitative analysis of macrophage differentiation in Raw264.7 cells treated with or without IL-4 (20 ng/mL) and transfected with si-scramble, si-circCdyl, or si-circCdyl together with si-IRF4. ∗∗p < 0.01; n = 5 per group. (B and D) Flow cytometry plots and quantitative analysis of macrophage differentiation in Raw264.7 cells treated with or without LPS (100 ng/mL) and IFN-γ (50 ng/mL) and transfected with si-scramble, si-circCdyl, or si-circCdyl together with si-IRF4. ∗∗p < 0.01; n = 5 per group.