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. 2021 Oct 19;30(2):763–781. doi: 10.1016/j.ymthe.2021.10.012

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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CD81–EGFR complex formation aided miR-34c-5p entry into fibroblasts and macrophages to downregulate CF and inhibit cellular activation

(A and B) The top two rows show representative images of vimentin (green) and α-SMA (red) staining, and F4/80 (green) and α-SMA (red) staining; bottom two rows show representative images of vimentin (green) and LCA (red) staining, and F4/80 (green) and LCA (red) staining. The bottom panel shows the quantification. Scale bar, 75 μm. Data are the mean ± SD (n = 6). Vimentin represents fibroblasts; F4/80 represents macrophages. (C) Representative images of EGFR (green), vimentin (red), and EGFR (green) and F4/80 (red) staining. The bottom panel shows the quantification. Scale bar, 75 μm. Data are the mean ± SD (n = 6). (D) Representative images of miR-34c-5p (fam) (green), vimentin (red), and miR-34c-5p (fam) (green) and F4/80 (red) staining. The bottom panel shows the quantification. Scale bar, 75 μm. Data are the mean ± SD (n = 6).