TABLE 1.

Effect of acupuncture on functional dyspepsia.

Year	Journal	Authors	Type of study	Sample size	Statistic value	Conclusion
2020	Evid Based Complement Alternat Med	Zhang et al.	Systemic review	3301	P ≤ 0.01	Five types of acupuncture (manual acupuncture, acupoint application, moxibustion, acupoint catgut embedding, and warm acupuncture alone) all were superior to prokinetics and sham acupuncture in terms of improving the symptoms of functional dyspepsia.
2020	World J Gastroenterol	Guo et al.	Systemic review	642	P < 0.05	Positive effects of acupuncture and EA were observed in regulating gastric motility, gastric accommodation, mental status, gastrointestinal hormones, and central and autonomic functions while improving dyspeptic symptoms and quality of life.
2017	Sci Rep	Ho et al.	Meta-analysis	1727	P ≤ 0.001	Manual acupuncture has marginally stronger effect in alleviating global FD symptoms, compared to domperidone or itopride.
2016	J Altern Complement Med	Zhou et al.	Meta-analysis	3097	P < 0.001	Acupuncture appears to be efficacious in relieving FD symptoms and improving quality of life
2016	Evid Based Complement Alternat Med	Pang et al.	Systemic review	1436	P ≤ 0.02	Acupuncture therapy achieves statistically significant effect for FD in comparison with sham acupuncture and is superior to medication (prokinetic agents) in improving the symptoms and quality of life of FD patients.
2015	Complement Ther Med	Kim et al.	Systemic review	1423	95% CI 1.85-3.82	Acupuncture treatment was associated with a significant positive effect in patients with functional dyspepsia
2014	Cochrane Database Syst Rev	Lan et al.	Systemic review	542	P > 0.05	It remains unknown whether manual acupuncture or electroacupuncture is more effective or safer than other treatments for patients with FD