Table. Summary of Findings (Mobile Stroke Unit vs Usual Care).
| Outcome | Pooled effect size (95% CI) | P value | I2, % | Studies (patients), No. |
|---|---|---|---|---|
| Excellent outcome, mRS score of 0-1 at 90 d | Adjusted OR, 1.64 (1.27-2.13) | <.001 | 48 | 5 (3228)16,20,21,35,37 |
| Crude OR, 1.37 (1.19-1.58) | <.001 | 0 | 5 (3228)16,20,21,35,37 | |
| Reduced disability, lower mRS score at 90 d | Adjusted common OR, 1.39 (1.14-1.70) | .001 | 0 | 3 (1563)16,20,35 |
| Crude common OR, 1.30 (1.12-1.50) | .001 | 21 | 5 (3228)16,20,21,35,37 | |
| Good outcome, mRS score of 0-2 at 90 d | Crude OR, 1.25 (1.09-1.44) | .001 | 0 | 6 (3266)16,20,21,35,37,41 |
| Proportion of IVT among patients with AIS | Crude OR, 1.83 (1.58-2.12) | <.001 | 13 | 7 (4790)12,16,20,21,34,35,39 |
| IVT within the golden hour | Crude OR, 7.71 (4.17-14.25) | <.001 | 75 | 8 (3351)16,20,21,36,37,38,40,42 |
| Onset-to-IVT time, min | Difference of medians, 31 (23-39) | <.001 | 47 | 13 (3322)12,13,16,20,21,34,35,37,38,39,40,41,42 |
| Alarm-to-IVT time, min | Difference of medians, 29 (25-33) | <.001 | 78 | 13 (3319)12,13,16,20,21,34,35,37,38,39,40,41,42 |
| Onset-to-MT time, min | Difference of medians, 27 (–17 to 71) | .23 | 86 | 5 (666)16,20,21,35,40 |
| Alarm-to-MT time, min | Difference of medians, 14 (–15 to 43) | .35 | 89 | 5 (671)16,20,21,35,40 |
| Death | ||||
| 7 d | Crude OR, 0.74 (0.51-1.09) | .13 | 33 | 9 (8599)12,13,16,20,21,34,35,37,42 |
| 90 d | Crude OR, 0.82 (0.58-1.17) | .28 | 56 | 7 (3924)16,20,21,34,37,41,42 |
| Symptomatic intracranial hemorrhage after IVT | Crude OR, 0.80 (0.52-1.24) | .32 | 0 | 5 (1977)16,20,37,41,42 |
| Stroke mimic among IVT-treated patients | Crude OR, 1.22 (0.70-2.14) | .48 | 0 | 3 (666)16,34,39 |
Abbreviations: IVT, intravenous thrombolysis; mRS, modified Rankin Scale; MT, mechanical thrombectomy; OR, odds ratio.