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. 2021 Mar 8;17:1744806921999924. doi: 10.1177/1744806921999924

Table 2.

Top 20 candidate SNPs selected from GWAS for all patients.

Model Rank CHR SNP Position P Related gene Genotype (patients)
Genotype (controls)
A/A A/B B/B A/A A/B B/B
Trend 1 8 rs10086452 3691292 0.00001026 CSMD1 2 48 141 18 107 156
Trend 2 16 rs12708686 25789460 0.00001532 HS3ST4 5 70 116 28 133 121
Trend 3 10 rs688391 6529658 0.00001721 PRKCQ 59 105 27 61 126 95
Trend 4 16 rs9989408 25786610 0.0000198 HS3ST4 8 76 107 34 140 108
Trend 5 4 rs4141270 106242441 0.00002805 44 95 52 33 126 122
Trend 6 4 rs10518617 133841275 0.00003039 29 84 78 15 107 159
Trend 7 20 rs4811012 48294701 0.00003177 3 58 130 22 116 144
Trend 8 15 rs6493688 29560167 0.00003323 40 89 62 25 124 133
Trend 9 12 rs10844159 32288782 0.00003414 BICD1 21 81 89 10 94 178
Trend 10 1 rs10803183 242444561 0.00003789 5 58 128 6 36 240
Trend 11 13 rs4773840 94568426 0.00004323 ABCC4 22 80 89 10 96 176
Trend 12 14 rs11621135 70729362 0.00004646 10 65 115 2 66 214
Trend 13 17 rs2958927 50314685 0.00004719 29 81 77 17 104 161
Trend 14 13 rs1678353 94547567 0.00004959 ABCC4 23 81 87 9 103 170
Trend 15 10 rs4749828 9062151 0.00004966 15 80 95 6 89 187
Trend 16 7 rs12700309 21850980 0.00005138 DNAH11 57 99 35 48 144 90
Trend 17 10 rs17784350 50512270 0.00005223 CHAT 7 61 123 25 127 130
Trend 18 2 rs2693818 6121959 0.0000536 31 80 79 59 166 57
Trend 19 11 rs6265 27636492 0.00005366 BDNF-AS1,BDNF 40 107 44 34 136 112
Trend 19 11 rs11030104 27641093 0.00005366 BDNF-AS1,BDNF 40 107 44 34 136 112
Dominant 1 2 rs2693818 6121959 0.0000009002 31 80 79 59 166 57
Dominant 2 2 rs6718476 6112647 0.0000009454 31 81 79 59 166 57
Dominant 3 10 rs688391 6529658 0.000001239 PRKCQ 59 105 27 61 126 95
Dominant 4 10 rs604663 6544132 0.000002684 PRKCQ 52 110 29 57 128 97
Dominant 5 1 rs10803183 242444561 0.000005297 5 58 128 6 36 240
Dominant 6 11 rs1488830 27593461 0.00003125 BDNF-AS1 53 107 31 54 134 94
Dominant 7 18 rs12964456 30023916 0.00003475 NOL4 17 56 118 20 143 118
Dominant 8 4 rs6531299 33872088 0.00003526 14 82 95 14 74 194
Dominant 9 20 rs6133220 551620 0.00003676 36 114 41 38 132 112
Dominant 10 2 rs941009 6058737 0.00003957 25 83 83 54 157 71
Dominant 11 1 rs6656194 164031638 0.00004554 33 98 60 29 111 142
Dominant 12 7 rs6461595 21724570 0.0000477 DNAH11 41 111 39 53 122 107
Dominant 13 8 rs2433150 6489560 0.00005107 5 40 146 13 104 165
Dominant 14 13 rs9532107 37187961 0.00005386 TRPC4 14 67 110 33 140 109
Dominant 15 2 rs10204095 57652544 0.0000553 5 37 148 10 101 166
Dominant 16 4 rs7670109 184691188 0.00005679 38 87 66 74 157 51
Dominant 17 6 rs13196989 184373 0.00005703 8 74 108 10 61 211
Dominant 18 3 rs7610425 150967983 0.00005804 ANKUB1 9 90 92 11 82 189
Dominant 19 2 rs12468070 6077432 0.00006067 25 84 82 56 155 71
Dominant 20 14 rs2167151 78933086 0.00006216 NRXN3 17 84 90 14 82 186
Recessive 1 1 rs4520412 15232554 0.0000008571 KAZN 25 110 56 92 115 75
Recessive 2 11 rs1519480 27632288 0.000002159 BDNF-AS1 0 61 130 25 101 156
Recessive 3 6 rs3777799 133631276 0.000003063 EYA4 22 54 111 4 93 185
Recessive 4 8 rs12545634 26929236 0.00001289 39 77 75 19 121 142
Recessive 5 2 rs10205827 75356361 0.00002183 10 102 79 52 122 107
Recessive 6 2 rs10208470 75356624 0.00002186 10 102 79 52 122 108
Recessive 7 7 rs12538837 97522404 0.00004215 27 111 53 86 128 68
Recessive 8 8 rs10086635 26955860 0.00004484 48 76 67 30 142 110
Recessive 9 4 rs6826653 19736139 0.00004904 15 55 121 2 84 196
Recessive 10 2 rs9309489 75355228 0.00004915 11 101 79 52 122 108
Recessive 11 10 rs2026432 6547609 0.00004948 PRKCQ 25 106 60 81 130 71
Recessive 12 13 rs9521844 110018508 0.00005096 0 61 130 19 94 169
Recessive 13 9 rs10959456 11002926 0.00005841 0 66 120 19 105 158
Recessive 14 8 rs9314506 3682052 0.00007367 CSMD1 25 102 64 80 131 71
Recessive 15 13 rs9555965 89459182 0.00007841 39 72 80 22 121 139
Recessive 15 13 rs9555966 89460007 0.00007841 39 72 80 22 121 139
Recessive 17 6 rs13203299 169184034 0.00008602 33 68 90 16 122 144
Recessive 18 11 rs12291063 27650677 0.00009339 BDNF-AS1,BDNF 0 53 138 18 92 172
Recessive 19 22 rs7290832 25658787 0.00009952 38 81 72 21 149 112
Recessive 20 9 rs871095 138095067 0.0001101 NACC2 41 93 57 24 145 113

Model, the genetic model in which candidate SNPs were selected by GWAS; CHR, chromosome number.Related gene, the nearest gene from the SNP site; A/A, homozygote for the minor allele in each SNP.A/B, heterozygote for the major allele in each SNP; B/B, homozygote for the major allele in each SNP.