Table 3.

Top 20 candidate SNPs selected from GWAS for patients with postherpetic neuralgia (PHN).

Model	Rank	CHR	SNP	Position	P	Related gene	Genotype (patients)			Genotype (controls)
							A/A	A/B	B/B	A/A	A/B	B/B
Trend	1	13	rs4773840	94568426	0.0000001638*	ABCC4	16	40	33	10	96	176
Trend	2	13	rs1678353	94547567	0.000000255	ABCC4	17	39	33	9	103	170
Trend	3	13	rs1751057	94548737	0.0000003913	ABCC4	17	39	33	10	102	170
Trend	4	13	rs1678395	94563955	0.000001063	ABCC4	16	40	33	11	101	170
Trend	5	13	rs1678362	94529692	0.000001482	ABCC4	16	41	32	12	103	167
Trend	5	13	rs1751052	94531379	0.000001482	ABCC4	16	41	32	12	103	167
Trend	5	13	rs1189438	94532991	0.000001482	ABCC4	16	41	32	12	103	167
Trend	8	9	rs10114508	26892593	0.000002803		5	36	46	2	63	214
Trend	9	13	rs1729752	94530363	0.000004509	ABCC4	18	39	32	14	108	160
Trend	10	13	rs4148540	94491368	0.000005799	ABCC4	13	45	31	16	94	172
Trend	10	13	rs4148540	94491368	0.000005799	ABCC4	4	42	43	66	136	80
Trend	12	18	rs12458523	19074726	0.00000617	CABLES1	11	43	35	14	82	186
Trend	13	14	rs2167151	78933086	0.000006287	NRXN3	6	44	39	6	80	196
Trend	14	12	rs10851014	117614600	0.0000063		16	39	34	12	105	165
Trend	15	13	rs1678387	94515907	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs1678365	94516981	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs1189451	94520087	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs2619312	94521040	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs1751037	94521559	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs1189461	94521789	0.000009474	ABCC4	16	39	34	12	105	165
Trend	15	13	rs1189464	94523867	0.000009474	ABCC4	16	39	34	12	105	165
Dominant	1	6	rs4075048	19275975	0.00001134		0	4	85	4	65	213
Dominant	2	14	rs2167151	78933086	0.00001212	NRXN3	11	43	35	14	82	186
Dominant	3	2	rs6718476	6112647	0.00001274		11	38	40	59	166	57
Dominant	3	2	rs2693818	6121959	0.00001274		11	38	40	59	166	57
Dominant	5	13	rs4148540	94491368	0.00001754	ABCC4	13	45	31	16	94	172
Dominant	6	6	rs9368038	19298240	0.00001905		0	5	84	5	66	211
Dominant	6	6	rs9350106	19303045	0.00001905		0	5	84	5	66	211
Dominant	8	12	rs10851014	117614600	0.00002548		6	44	39	6	80	196
Dominant	9	2	rs4675047	226665422	0.00002799		3	24	62	29	125	119
Dominant	10	1	rs2176360	188083580	0.00002889		9	50	30	14	100	168
Dominant	11	7	rs4722067	21868091	0.00003014	DNAH11	16	33	40	82	140	60
Dominant	12	16	rs12596324	26039779	0.00003039	HS3ST4	10	29	50	44	150	88
Dominant	13	6	rs9358193	19281466	0.0000309		0	5	84	5	64	211
Dominant	14	6	rs648248	117187750	0.00003254	FAM162B	13	30	46	48	157	77
Dominant	15	9	rs10114508	26892593	0.00003959		5	36	46	2	63	214
Dominant	16	13	rs4773840	94568426	0.00004453	ABCC4	16	40	33	10	96	176
Dominant	17	8	rs7822451	17266781	0.00004517	MTMR7	5	29	55	35	143	104
Dominant	18	7	rs10278297	135341940	0.00004885		15	33	41	49	168	65
Dominant	19	1	rs624912	236807876	0.00005329		7	21	61	32	126	123
Dominant	20	8	rs2658914	56511974	0.00005364	XKR4	0	18	71	13	111	158
Recessive	1	13	rs1678353	94547567	0.00000369	ABCC4	17	39	33	9	103	170
Recessive	2	13	rs1751057	94548737	0.000008018	ABCC4	17	39	33	10	102	170
Recessive	3	18	rs12458523	19074726	0.00001884	CABLES1	4	42	43	66	136	80
Recessive	4	13	rs4773840	94568426	0.00002414	ABCC4	16	40	33	10	96	176
Recessive	5	12	rs10849659	118331044	0.00002555	CCDC60	19	28	42	15	132	135
Recessive	6	13	rs1729752	94530363	0.00003901	ABCC4	18	39	32	14	108	160
Recessive	7	2	rs10208470	75356624	0.00004381		2	49	38	52	122	108
Recessive	8	2	rs10205827	75356361	0.00004401		2	49	38	52	122	107
Recessive	9	12	rs4465416	118338125	0.00004502	CCDC60	19	28	42	16	131	135
Recessive	10	13	rs9576139	36396944	0.00004547		0	37	52	36	108	138
Recessive	11	13	rs1678395	94563955	0.0000476	ABCC4	16	40	33	11	101	170
Recessive	12	12	rs4300442	118324515	0.00005037	CCDC60	20	29	40	17	131	134
Recessive	13	2	rs1015802	153792446	0.00005759		8	20	60	1	77	204
Recessive	14	2	rs11680628	153839089	0.00006176		8	20	61	1	75	206
Recessive	15	2	rs1439630	153839620	0.00006204		10	24	55	3	82	197
Recessive	15	2	rs7556698	153850240	0.00006204		10	24	55	3	81	198
Recessive	17	9	rs10981230	113851385	0.00007136	MIR3134,SUSD1	35	38	16	50	152	80
Recessive	18	13	rs9557470	100094751	0.00007228	TMTC4	23	31	35	24	130	128
Recessive	19	1	rs4129058	5310402	0.00007338		2	59	28	50	131	101
Recessive	20	4	rs7670109	184691188	0.00008034		35	37	17	51	157	74

Model, the genetic model in which candidate SNPs were selected by GWAS; CHR, chromosome number.Related gene, the nearest gene from the SNP site; A/A, homozygote for the minor allele in each SNP.A/B, heterozygote for the major allele in each SNP; B/B, homozygote for the major allele in each SNP.*, Significant association after correction for multiple testing.