Figure 2.

Plots of oxygen uptake, Δ[O₂], recorded during the peroxidation of 2.74 mM MeLin in LUVs composed of DMPC and DMPG at a molar ratio of 3:1. Uninhibited peroxidation (dashed line, described as “spontaneous” process); peroxidation inhibited by 1 μM PMHC (solid line) or 5 μM DA (dash–dotted line). R_ox1, rate of uninhibited oxidation; R_inh, rate of the process during the inhibition period (the end of this period is indicated as τ_ind); R_ox2, rate of the postinhibited process (after τ_ind). The values of parameters R_ox1, R_inh, τ_ind, and R_ox2 are listed in Table S6. Experiments were performed at 310 K and pH 7.0 with 10 mM ABAP used to initiate the peroxidation of MeLin.