TABLE 3.
Statistical values obtained from the 3-way repeated measures ANOVA for Figure 5c and d (dopamine) and 6c and d (glutamate)
| Analysis | Value | Exact F | Num DF | DenDF | Prob > F | |
|---|---|---|---|---|---|---|
| DA 40–100 | ||||||
| Between | All | 0.9098 | 3.6391 | 3 | 12 | 0.0448* |
| Intercept | 16.1377 | 193.6523 | 1 | 12 | <0.0001 | |
| Housing | 0.0766 | 0.9189 | 1 | 12 | 0.3567 | |
| CP-154,256 | 0.2099 | 2.5191 | 1 | 12 | 0.1385 | |
| Housing × CP | 0.4833 | 5.8001 | 1 | 12 | 0.0330* | |
| Within | All (Roy’s Max Root) | 3.3337 | 5.0006 | 6 | 9 | 0.0160* |
| Time | 5.8165 | 6.7859 | 6 | 7 | 0.0118* | |
| Time × Hous | 0.9485 | 1.1066 | 6 | 7 | 0.4425 | |
| Time × CP | 0.5893 | 0.6876 | 6 | 7 | 0.6679 | |
| Time × Hous × CP | 1.5890 | 1.8539 | 6 | 7 | 0.2190 | |
| DA 40–60 | ||||||
| Between | All | 1.6472 | 6.5888 | 3 | 12 | 0.0070* |
| Intercept | 33.6560 | 403.8719 | 1 | 12 | <0.0001* | |
| Housing | 0.3265 | 3.9182 | 1 | 12 | 0.0712 | |
| CP-154,256 | 1.2123 | 14.5481 | 1 | 12 | 0.0025* | |
| Housing × CP | 0.2130 | 2.5566 | 1 | 12 | 0.1358 | |
| Within | All (Roy’s Max Root) | 0.5033 | 2.0135 | 3 | 12 | 0.1658 |
| Time | 0.0820 | 0.4511 | 2 | 11 | 0.6482 | |
| Time × Hous | 0.1516 | 0.8341 | 2 | 11 | 0.4600 | |
| Time × CP | 0.1682 | 0.9254 | 2 | 11 | 0.4252 | |
| Time × Hous × CP | 0.2737 | 1.5055 | 2 | 11 | 0.2643 | |
| Glut 40–100 | ||||||
| Between | All | 0.7434 | 2.9738 | 3 | 12 | 0.0743 |
| Intercept | 10.5268 | 126.3224 | 1 | 12 | <0.0001* | |
| Housing | 0.7083 | 8.5005 | 1 | 12 | 0.0129* | |
| CP-154,256 | 0.0129 | 0.1546 | 1 | 12 | 0.7010 | |
| Housing × CP | 0.0126 | 1.5093 | 1 | 12 | 0.2428 | |
| Within | All (Roy’s Max Root) | 7.0672 (ap) | 10.6009 | 6 | 9 | 0.0012* |
| Time | 4.3122 | 5.0309 | 6 | 7 | 0.0261* | |
| Time × Hous | 3.6935 | 4.3092 | 6 | 7 | 0.0385* | |
| Time × CP | 0.4979 | 0.5809 | 6 | 7 | 0.7374 | |
| Time × Hous × CP | 5.1888 | 6.0536 | 6 | 7 | 0.0161* | |
| GLU 40–60 | ||||||
| Between | All | 0.8780 | 3.5186 | 3 | 12 | 0.0490* |
| Intercept | 16.9956 | 203.9481 | 1 | 12 | <0.0001* | |
| Housing | 0.5639 | 6.7672 | 1 | 12 | 0.0232* | |
| CP-154,256 | 0.1895 | 2.2735 | 1 | 12 | 0.1575 | |
| Housing × CP | 0.2828 | 3.3937 | 1 | 12 | 0.0903 | |
| Within | All (Roy’s Max Root) | 0.2951 | 1.1805 | 3 | 12 | 0.3581 |
| Time | 0.0150 | 0.0829 | 2 | 24 | 0.9210 | |
| Time × Hous | 0.0668 | 0.3676 | 2 | 24 | 0.7006 | |
| Time × CP | 0.0231 | 0.1269 | 2 | 24 | 0.8821 | |
| Time × Hous × CP | 0.2782 | 1.5304 | 2 | 24 | 0.2592 | |
*
A three way MANOVA indicates that extracellular DA levels in the NAc are significantly different between single-housed and group-housed animals. DA levels were also different between animals that received the CRF antagonist and those that received the vehicle.