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. 2022 Jan 25;8:808233. doi: 10.3389/fvets.2021.808233

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Copyright © 2022 Bao, Liang, Sun, Mohyuddin, Chen, Wen, Yong, Ma, Yu, Ju and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of baicalin on key proteins in the Nrf2 signaling pathway in LPS-stimulated IPEC-J2 cells. Immunofluorescence detection of nuclear Nrf2 protein import in IPEC-J2 cells (A). Western blotting was used to determine the expression of HO-1, Nrf2, β-actin, and lamin B (B). Cytoplasmic and nuclear Nrf2 protein expression (C). Data are presented as the mean ± SEM (n = 3 per treatment, *p < 0.05 compared with the model group). CON, control; L-Bai, low-concentration baicalin; M-Bai, middle-concentration baicalin; H-Bai, high-concentration baicalin.