Table 1.
Characteristics of the patient subgroups infected with different M. tuberculosis genotypes
| Characteristics |
Beijing N (%) |
Modern Beijing | Ancient Beijing |
non- Beijing N (%) |
TOTAL N (%) |
||||
|---|---|---|---|---|---|---|---|---|---|
| B0/W148-cluster | Central Asian Russian | 1071–32-cluster | 14717–15-cluster | ||||||
| Total | 370 (67.5%) | 102 (18.6%) | 219 (40.0%) | 37 (6.7%) | 12 (2.2%) | 178 (32.5%) | 548 (100%) | ||
| Gender | |||||||||
| Male | 265 (71.7%) | 77 (75.5%) | 151 (68.9%) | 28 (75.7%) | 9 (75.0%) | 128 (71.9%) | 393 (71.7%) | ||
| Female | 105 (28.3%) | 25 (24.5%) | 68 (31.1%) | 9 (24.3%) | 3 (25.0%) | 50 (28.1%) | 155 (28.3%) | ||
| Age, years old | |||||||||
| 18–34 | 139 (37.6%) | 42 (41.2%) | 78 (35.6%) | 14 (37.8%) | 5 (41.7%) | 60 (33.7%) | 199 (36.3%) | ||
| 35–44 | 128 (34.6%) | 36 (35.3%) | 73 (33.3%) | 13 (35.2%) | 5 (41.7%) | 51 (28.7%) | 179 (32.7%) | ||
| 45–54 | 51 (13.8%) | 13 (12.7%) | 33 (15.1%) | 6 (16.2%) | 0 | 23 (12.9%) | 74 (13.5%) | ||
| ≥ 55 | 52 (14.0%) | 11 (10.8%) | 35 (16.0%) | 4 (10.8%) | 2 | 44 (24.7%) | 96 (17.5%) | ||
| Urban | 211 (57.0%) | 62 (60.8%) | 122 (55.7%) | 20 (54.0%) | 6 (50.0%) | 100 (56.2%) | 311 (56.7%) | ||
| Rural | 159 (43.0%) | 40 (39.2%) | 96 (44.3%) | 17 (46.0%) | 6 (50.0%) | 78 (43.8%) | 237 (43.2%) | ||
| HIV-positive | 143 (38.6%) | 39 (38.2%) | 83 (37.9%) | 16 (43.2%) | 5 (41.7%) | 49 (27.5%) | 192 (35.0%) | ||
| HIV-negative | 227 (61.4%) | 63 (62.8%) | 136 (62.1%) | 21 (56.8%) | 7 (58.3%) | 129 (72.5%) | 356 (65.0%) | ||
| Clinical forms of tuberculosis (based on clinical and X-ray characteristics) | |||||||||
| Focal TB of lungs | 6 (1.6%) | 3 (2.9%) | 2 (0.9%) | 0 | 1 (8.3%) | 5 (2.8%) | 11 (2.0%) | ||
| Infiltrative TB of lungs | 258 ( 69.7%) | 68 (66.7%) | 157 (71.7%) | 22 (59.5%) | 11 (91.7%) | 126 (70.8%) | 384 (70.0%) | ||
| Fibrous-cavernous TB | 22 (5.9%) | 8 (7.9%) | 9 (4.1%) | 5 (13.5%) | 0 | 11 (6.2%) | 33 (6.1%) | ||
| Disseminated TB of lungs | 56 (15.1%) | 16 (15.7%) | 34 (15.5%) | 6 (16.2%) | 0 | 26 (14.6%) | 82 (15.0%) | ||
| Other | 27 (7.6%) | 7 (6.8%) | 17 (7.8%) | 4 (10.8%) | 0 | 10 (5.6%) | 38 (6.9%) | ||
| M. tuberculosis drug resistance | |||||||||
| MDR | 209 (56.5%) | 92 (90.2%) | 72 (32.9%) | 37 (100%) | 12 (100%) | 38 (21.4%) | 247 (45.1%) | ||
| Other resistance | 47 (12.7%) | 10 (9.8%) | 37 (16.9%) | 0 | 0 | 22 (12.3%) | 69 (12.6%) | ||
| Susceptible | 114 (30.8%) | 0 | 110 (50.2%) | 0 | 0 | 118 (66.3%) | 232 (42.3%) | ||
| Lethal outcome due to TB | 118 (31.9%) | 32 (31.4%) | 65 (29.7%) | 14 (37.8%) | 7 (58.3%) | 27 (15.2%) | 145 (26.5%) | ||