Table 1.
Effect of FREG on TNBS induced alterations in colon weight to length ratio, macroscopic scores & DAI scores in rats. Colon weight to length ratio, macroscopic and DAI scores were decreased significantly after treatment with FREG. Data were expressed as the mean ± SD; n = 6. ★P < 0.05 significantly different from normal control group. #P < 0.05 significantly different from TNBS control group
| Treatment Groups | Colon weight to length ratio (mg/cm) | Macroscopic scores | DAI scores |
|---|---|---|---|
| Normal control | 101.48 ± 5.03 | 0.17 ± 0.41 | 0.00 ± 0.00 |
| TNBS dose 25 mg | 180.72 ± 22.49★ | 4.00 ± 1.26★ | 1.33 ± 0.0★ |
| Mesacol 250 mg/kg | 134.12 ± 8.47# | 0.50 ± 0.55# | 0.11 ± 0.27# |
| FREG 6.25 mg/kg | 123.53 ± 9.73# | 1.00 ± 0.89# | 0.39 ± 0.61 |
| FREG 12.5 mg/kg | 133.07 ± 13.94# | 0.50 ± 0.55# | 0.22 ± 0.54# |
| FREG 25 mg/kg | 142.17 ± 22.10# | 0.50 ± 0.55# | 0.22 ± 0.35# |