Fig. 1.

Design and assessment of the transcription regulation unit. a Design of the transcription repression unit. b Evaluation of the ability of selected splits to repress the transcription. c Flow cytometry for the 166 split-site under the transcription repression unit. (Grey: control no GFP; green: 166 split-site under the light condition and dark green: represent the 166 split-site under dark state. d Design of the transcription activation unit. e Evaluation of the transcription activation unit. f Flow cytometry for 166 split-site under the transcription activation unit. (Grey: control no GFP; green: 166 split-site under the light condition and dark green: represent the 166 split-site under dark state). The numbers above the bars indicate the fold change, calculated from the fluorescence ratio between the dark and the light phases