Fig. 2.

Overall structure of the K1 lyase. a The gene encoding a polysaccharide depolymerase (PDP) in the genome of bacteriophage NTUH-K2044-K1-1. The arrows represent the open reading frames 20–35 of the genome [15]. The polysaccharide depolymerase contains distinct domains, as described below, with the amino acid residues in the domains being further indicated. b, c and d The trimeric structure of the enzyme drawn as three-colored ribbons in top, bottom and side view, respectively. The bound trisaccharides at the solvent-accessible groove of individual subunits and the inter-subunit pockets are shown as yellow and cyan sphere models, respectively. The view in d is perpendicular to the trimer axis onto a solvent-accessible groove with the N-terminal end on top. A transparent surface is also shown. e Structure of individual subunit of K1 lyase. The domains are further indicated with colors as in a