Title	The Transitions to Long-term In Home Ventilator Engagement Study (Transitions to LIVE): study protocol for a pragmatic randomised controlled trial
Trial registration {2a and 2b}.	ClinicalTrials.gov: NCT04180722
Protocol version {3}	Version 3; March 16, 2021
Funding {4}	Canadian Institutes of Health Research (CIHR), reference number TC2-165734
Author details {5a}	1 The Hospital for Sick Children, 555 University Ave, Toronto, Canada M5G 1X8 2 Institute for Health Policy, Management, and Evaluation, University of Toronto, 155 College St 4th Floor, Toronto, Canada, M5T 3 M6 3 Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Canada M4N 3 M5 4 ICES, 2075 Bayview Ave, Toronto, Canada M4N 3 M5 5 Ontario Child Health Support Unit, The Hospital for Sick Children, 555 University Ave, Toronto, Canada M5G 1X8 6 Ontario Ventilator Equipment Pool, Kingston Health Sciences Centre 640 Cataraqui Woods Dr, Kingston, Canada K7P 2Y5 7 Department of Health Metric Sciences, University of Washington, Seattle, WA 98105, United States 8 Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Canada M4N 3 M5 9 Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King’s College London, James Clerk Maxwell Building, 57 Waterloo Road, London, United Kingdom, SE1 8WA 10 Critical Care Directorate and Lane Fox Respiratory Unit, Guy's and St Thomas’ NHS Foundation Trust, Westminster Bridge Road, London, United Kingdom, SE1 7EH
Name and contact information for the trial sponsor {5b}	Ramune Pleinys The Hospital for Sick Children, Toronto Ontario 555 University Ave, Toronto, Canada M5G 1X8
Role of sponsor {5c}	The role of the sponsor includes institutional indemnity insurance for the trial but does not include funding or conduct of the trial.
Composition, Roles and Responsibilities {5d}	The core study team (PI: RA) and two research coordinators will run the trial on a daily basis. The broader research team including site PIs, research team members, local HMV members, and patient and family stakeholders meet monthly at investigator meetings and ad hoc as needed for site specific meetings. These meetings are to provide study updates, troubleshoot issues, and support ongoing engagement of the team. The Trial Steering Committee will be meet twice a year during the study period.