Table 2.
Lifetime risk (%) with 95% confidence interval of individual and composite major adverse renal and cardiovascular events by baseline disease status in T2D
| Baseline status | Outcomes | ||||||
|---|---|---|---|---|---|---|---|
| HF | CKD | MI | Stroke | PAD | CVD death | MARCE | |
| Reference: CVRD free | 29.2 (27.5–29.7) | 53.6 (52.6–54.1) | 18.9 (17.2–19.3) | 20.2 (18.5–20.6) | 9.2 (8.1–9.5) | 40.5 (40.0–41.1) | 80.0 (79.7–80.4) |
| HF only | – | 66.0 (65.2–70.6) | 25.7 (21.6–29.4) | 18.7 (13.2–21.7) | 12.8 (8.8–15.5) | 66.0 (65.0–69.4) | 97.1 (97.1–100) |
| CKD only | 34.7 (32.9–36.2) | – | 20.7 (18.7–22.0) | 20.3 (18.2–21.6) | 13.0 (11.2–14.3) | 45.7 (44.3–47.2) | 93.3 (93.3–96.3) |
| MI only | 44.0 (37.2–49.8) | 53.2 (49.1–58.8) | – | 24.4 (15.9–28.1) | 14.3 (9.1–17.9) | 60.3 (56.1–64.4) | 97.6 (97.6–100) |
| Stroke only | 28.8 (25.5–30.5) | 54.5 (52.9–56.7) | 23.8 (20.4–25.8) | – | 12.3 (10.2–13.6) | 56.2 (54.7–57.9) | 89.2 (89.1–92.1) |
| PAD only | 35.2 (30.0–38.4) | 56.0 (53.8–61.4) | 29.2 (21.4–33.7) | 27.7 (21.0–31.8) | – | 52.5 (49.0–56.0) | 90.8 (90.8–98.9) |
Abbreviations: HF heart failure, CKD chronic kidney disease, CVD cardiovascular disease, MI myocardial infarction, MARCE major adverse renal cardiovascular events, PAD peripheral artery disease