Fig. 14.

Blockade of Nrf2 abolished the antidepressant and anxiolytic effects of EDA. A Schematic timeline of the experimental procedure. B Social interaction test. C Sucrose preference test. D Open field test. E Elevated plus maze test. F Tail suspension test. G Forced swimming test. H Novel object recognition test. All the data are expressed as mean ± SEM (n = 8 per group). **p < 0.01, ***p < 0.001 versus the CON group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 versus the CSDS group. ^&p < 0.05 versus the CSDS + EDA group