Fig. 4.

Administration of EDA increased the expression of TREM2 and GFAP. A, B Immunofluorescence staining of TREM2 in the Hip. Scale bar, 50 μm. C, D Immunofluorescence staining of TREM2 in the mPFC. Scale bar, 50 μm. E, F Concentrations of Trem2 and GFAP in the Hip. G, H Concentrations of TREM2 and GFAP in the mPFC. Data are presented as mean ± SEM (n = 3 per group for immunostaining experiments, n = 6 mice for ELISA). **p < 0.01, ***p < 0.001 versus the CON + Vehicle group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 versus the CSDS + Vehicle group