Table II.
Baseline cfDNA levels and tumor response according to RECIST version 1.1.
Best response | Total (n=45)a | <75th percentile (n=33) | ≥75th percentile (n=12) |
---|---|---|---|
DC (PR+SD) | 35(78) | 30(91) | 5 (42%) |
PD | 10(22) | 3(9) | 7 (58%) |
P=0.001 according to Fisher's exact test. The total cohort (n=47) was dichotomized acccording to the 75th percentile of cfDNA levels at baseline.
aFor two patients, the first response evaluation had not yet been performed. cfDNA, cell-free DNA; DC, disease control; PR, partial response; SD, stable disease; PD, progressive disease.