Table 5:
Model 1: Disease Status (n=88) | HR | 95% CI | P |
ETP | 0.98 | 0.6–1.7 | 0.9 |
CR2+ | 1.6 | 0.8–3.3 | 0.2 |
PIF/CR1 | 2.9 | 1.1–7.5 | 0.03 |
No CR | 3.5 | 1.5–7.9 | 0.003 |
Model 2: MRD Status (n=64) |
HR | 95% CI | P |
ETP | 0.7 | 0.3–1.6 | 0.4 |
MRD Positive | 2.8 | 1.3–5.9 | 0.006 |
CR status and MRD status were highly correlated variables, so each variable was evaluated independently on multivariate analysis. 88 patients had known T-ALL subtype data, and were considered in model 1. 64 patients had known MRD data by flow cytometry after 2004, when flow cytometry assessment prior to transplant became routine.