Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 4;15:345–358. doi: 10.2147/DMSO.S346097

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Pramanik et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

(A) Positive regulation of transcription by RNA polymerase II (GO: 0045944, no of genes 34), Cytokine-mediated signalling pathway (GO:0019221, 20), Cellular response to hypoxia (GO:0071456, 12), Ras protein signal transduction (GO:0007265, 10), Apoptotic process (GO:0006915, 22), Cell cycle (GO:0007049, 18), Insulin receptor signalling pathway (GO:0008286, 8), Response to insulin (GO:0032868, 7), Response to hypoxia (GO:0001666, 9), Positive regulation of angiogenesis (GO:0045766, 8), Angiogenesis (GO:0001525, 8), Inflammatory response (GO:0006954, 9) and Response to oxidative stress (GO:0006979, 5). (B) Representative image of relevant KEGG pathways significantly enriched with validated targets of miR-126 and miR-132: From left to right FoxO signalling pathway (hsa04068, number of genes 16), Chemokine signalling pathway (hsa04062, 17), HIF-1 signalling pathway (hsa04066, 13), VEGF signalling pathway (hsa04370, 11), AGE-RAGE signalling pathway in diabetic complications (hsa04933, 12), Insulin signalling pathway (hsa04910, 12), Apoptosis (hsa04210, 11), Insulin resistance (hsa04931, 9), Cell cycle (hsa04110, 8), Carbohydrate digestion and absorption (hsa04973, 5), Adipocytokine signalling pathway (hsa04920, 6), TGF-beta signalling pathway (hsa04350, 6) and Type II diabetes mellitus (hsa04930,5).