Receiver operating characteristic curves and area under the receiver
operating characteristic curves (AUCs) for each lung deformable
registration algorithm for predicting Global Initiative for Chronic
Obstructive Lung Disease (GOLD) stages with use of percentage emphysema
low attenuation area, or %EM-LAA, and percentage air
trapping–attenuation difference map, or %AT-ADM, as predictors.
Algorithms showed near-identical performance for each respective GOLD
stage. Areas under the receiver operating characteristic curves for the
algorithm for performing deformable registration of lung CT (LungReg)
were not significantly different from those for symmetric diffeomorphic
registration (iterative) (SyN), which suggests that LungReg air trapping
measurements could supplant SyN air trapping measurements.