Figure 3.

Brachial artery flow-mediated dilation in response to inhibition of vascular oxidative stress via an acute supraphysiologic infusion of ascorbic acid. Brachial artery flow-mediated dilation following an acute supraphysiologic infusion of ascorbic acid known to inhibit superoxide production or isovolumetric saline at baseline (left) and following 12 months (right) of treatment with curcumin (A) or placebo (B). These measures were performed in a subgroup of participants ≥18 years of age. *P<0.05 by paired t test comparing saline with vitamin C within a single group at a single time point.