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PFD treatment decreases TGF-β production and recruitment of immunosuppressive MDSCs in tumors.
(A) PFD decreases serum TGF-β1 in renal cancer-bearing mice. (B) Flow cytometry analysis and (C) quantification of tumor-infiltrating MDSCs indicate that PFD treatment affects the immunosuppressive tumor microenvironment. Data represents the means ± SD. *P < .05; **P < .01; ***P < .001.
