Figure 1.

Circulating microbiome comparison between controls and liver cirrhosis patients.

a) Bar plot representing different phylum relative abundances in peripheral blood of liver cirrhosis patients and controls. b) Shannon diversity index (α-diversity) stratified by diagnosis. c) Blood microbiome community composition (β-diversity) assessed by non-multidimensional scaling on Bray-Curtis dissimilarity, with significant clustering according to diagnosis. d and e) Differential relative abundance testing between liver cirrhosis patients and controls: Taxa with significantly different relative distribution on Family (D) and Genus (E) levels are displayed by volcano plots. The x‐axis shows the log2 fold change, y‐axis displays the – log 10 transformed P‐value. Taxa were considered differentially abundant when reaching a Padj <0.05 and absolute log 2-fold change > 1