Figure 6.

Circulating microbiome and prediction of portal hypertension.

Circulating microbiome ability to discriminate patients with clinically significant and severe portal hypertension. Genera used in prediction model were selected based on DESeq2 results: Relative abundances of Bacteroides+Enhydrobacter+Escherichia/Shigella+Corynebacterium were used to discriminate patients with clinically significant portal hypertension, while Prevotella+Bacteroides+Enhydrobacter+Escherichia/Shigella+Corynebacterium+Alistipes – patients with severe portal hypertension. The values in brackets indicate the 95% confidence interval. AUC – area under the receiver operating characteristic curve; PH – portal hypertension.