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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Hypertension. 2021 Nov 10;78(6):1701–1710. doi: 10.1161/HYPERTENSIONAHA.121.17682

Table 3.

Incidence of Probable Dementia and Mild Cognitive Impairment by Treatment Group*

Treatment Group
Intensive Standard
Outcomes # with Outcomes/ Person-Years Cases/ 1000 person-years # with Outcomes/ Person-Years Cases/ 1000 person-years Hazard Ratio
(95% CI)a
P value
Probable Dementia 149 / 20,569 7.2 176 / 20,378 8.6 0.83 (0.67 – 1.04) 0.10
Mild Cognitive Impairment 287 / 19,690 14.6 352 / 19,281 18.3 0.81 (0.69 – 0.95) 0.007
Composite of Mild Cognitive Impairment or Probable Dementia 402 / 19,873 20.2 468 / 19,488 24.1 0.85 (0.74 – 0.97) 0.01
*

Includes data during trial treatment intervention ending August 20, 2015 and that collected during extended observational follow-up between October 2017 and July 2018. Williamson JD, et al. JAMA. 2019;321(6):553–561.