Table 3.
Summary of unsolicited adverse events by treatment arm and injections (safety analysis set).
| First injection |
Second injection |
Any injection |
||||
|---|---|---|---|---|---|---|
| n (%) | mRNA-1273 (N = 150) |
Placebo (N = 50) |
mRNA-1273 (N = 147) |
Placebo (N = 50) |
mRNA-1273 (N = 150) |
Placebo (N = 50) |
| Any unsolicited adverse event | 31 (20.7) | 9 (18.0) | 27 (18.4) | 7 (14.0) | 45 (30.0) | 11 (22.0) |
| Maximum severity | ||||||
| Grade 1 | 21 (14.0) | 8 (16.0) | 21 (14.3) | 3 (6.0) | 29 (19.3) | 7 (14.0) |
| Grade 2 | 10 (6.7) | 1 (2.0) | 6 (4.1) | 4 (8.0) | 16 (10.7) | 4 (8.0) |
| Grade ≥ 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| Relationship to intervention | ||||||
| Not related | 21 (14.0) | 8 (16.0) | 7 (4.8) | 7 (14.0) | 18 (12.0) | 10 (20.0) |
| Related | 10 (6.7) | 1 (2.0) | 20 (13.6) | 0 | 27 (18.0) | 1 (2.0) |