Table 1.

Overall variations of nucleotide numbers at different codon positions.

Lineage	Codon position	C	G	A	U
S	1	−3.5	−0.3	−0.9	+4.7
	2	−5.0	+1.3	+0.1	+3.6
	3	−4.7	−1.2	+1.1	+4.8
L	1	0.0	−0.4	+0.4	0.0
	2	−0.6	−0.4	+0.3	+0.7
	3	−0.4	+0.1	−0.3	+0.6
V	1	−0.6	+0.2	−0.4	+0.7
	2	−0.3	0.0	−0.3	+0.5
	3	−0.3	+0.5	−0.1	−0.1
G	1	−1.2	−0.6	−0.1	+1.9
	2	−1.3	+0.4	−0.1	+1.0
	3	−0.1	−0.3	−0.1	+0.5
GH	1	−1.7	−0.9	−0.2	+2.8
	2	−4.6	+0.4	+0.1	+4.1
	3	−2.2	−1.0	+0.4	+2.8
GR	1	−1.1	+0.5	−1.3	+1.9
	2	−4.3	+0.1	+1.3	+3.0
	3	−2.2	−0.5	−0.3	+2.9
GV	1	−0.8	−1.0	−0.1	+1.8
	2	−1.1	0.0	0.0	+1.2
	3	−1.1	−0.9	0.0	+2.0
Alpha	1	−0.5	−0.7	0.0	+1.2
	2	−1.0	0.0	−0.1	+1.2
	3	−1.8	−0.7	−0.1	+2.5
Beta	1	−0.8	−0.3	−0.2	+1.3
	2	−0.7	+0.1	0.0	+0.6
	3	−1.0	−0.5	−0.4	+1.9
Gamma	1	−0.3	+0.2	−0.5	+0.6
	2	−2.3	0.0	+0.3	+2.0
	3	−1.3	0.0	−0.2	+1.5
Delta	1	−0.2	−2.2	−0.7	+3.2
	2	−2.4	+0.4	−0.6	+2.6
	3	−2.0	+0.5	−0.2	+2.7
Omicron	1	0.0	0.0	0.0	0.0
	2	0.0	0.0	0.0	0.0
	3	−0.2	−0.1	0.0	+0.3

This table lists increased (+) or reduced (−) number of nucleotides at different codon positions over the survey period. Please refer to Table S3 (values within green frame) for detailed data.

This table lists increased (+) or reduced (−) number of nucleotides at different codon positions over the survey period. Please refer to Table S3 (values within green frame) for detailed data.