TABLE 9.
Drug | ADR | ROR | 95% CI lower limit | PRR | 95% CI lower limit | χ2 |
---|---|---|---|---|---|---|
Pembrolizumab | Pneumonitis | 39.93 | 8.28 | 28.25 | 8.77 | 104632.48 |
Rituximab | Urticaria | 10.49 | 1.08 | 10.27 | 1.09 | 16193.88 |
Sintilimab | Hepatic failure a | 6.96 | 1.61 | 6.59 | 1.62 | 9109.80 |
Sintilimab | Hyperthyroidism | 9.49 | 2.46 | 8.78 | 2.48 | 6804.49 |
Camrelizumab | Hyperthyroidism | 7.74 | 2.02 | 7.27 | 2.03 | 5081.48 |
Camrelizumab | Pneumonitis | 4.74 | 1.15 | 4.54 | 1.16 | 5049.10 |
Camrelizumab | Hypothyroidism | 9.87 | 2.76 | 9.09 | 2.79 | 3780.48 |
Bevacizumab | Hypertension | 12.35 | 3.53 | 11.32 | 3.55 | 1691.69 |
Nimotuzumab | Fever | 5.91 | 1.29 | 3.80 | 1.50 | 457.11 |
Bevacizumab | Vomiting | 3.28 | 1.36 | 3.04 | 1.38 | 197.76 |
Trastuzumab | Vomiting | 2.27 | 1.01 | 2.18 | 1.03 | 73.28 |
Sintilimab | Rash | 2.63 | 1.23 | 2.29 | 1.26 | 42.36 |
Rituximab | Dyspnea | 5.15 | 2.30 | 4.67 | 2.33 | 22.22 |
Trastuzumab | Chills | 3.74 | 2.17 | 3.18 | 2.22 | 5.98 |
Off-label ADR.