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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Neurosurg. 2021 Jul 16;136(1):88–96. doi: 10.3171/2021.1.JNS203536

FIG. 2.

FIG. 2.

Correlations between age and brain metastasis subtype for individual neuroanatomical lobes. Given the predicted regionalization of metastasis by cancer subtype, we further examined whether age differentiation was observed. A: Breast cancer patients with frontal lobe metastasis were significantly younger than patients with colon (p = 0.0003), lung (p < 0.0001), and renal (p = 0.0007) metastasis in the frontal lobe. Furthermore, melanoma patients with frontal lobe metastasis were significantly younger than patients with lung (p = 0.0002) and colon (p = 0.0080) metastasis in the frontal lobe. B: Among those with parietal lobe metastasis, breast cancer patients were significantly younger than patients with colon (p = 0.0204), lung (p < 0.0001), melanoma (p = 0.0459), and renal cell (p = 0.0049) tumors, and lung cancer patients were significantly older than patients with melanoma (p = 0.0301). C: Similarly, among those with temporal lobe metastasis, lung cancer patients were significantly older than melanoma patients (p = 0.0044). D: Among those with occipital lobe metastasis, lung cancer patients were significantly older than patients with breast cancer (p = 0.0010) and melanoma (p = 0.0205). E: Among those with cerebellar metastasis, breast cancer patients were significantly younger than patients with colon (p = 0.0018), lung (p < 0.0001), and melanoma (p < 0.0001) tumors. Figure is available in color online only.