Figure 5.
The amplitude of the α1-AR-EPSC does not determine the time course of signaling. A, Example traces of the α1-AR-EPSC in three different neurons demonstrating similar amplitudes but different decay kinetics. B, There was no correlation between amplitude of the α1-AR-EPSC and the activation kinetics (τ-activation, p = 0.999, n = 44 pairs). C, There was no correlation between the amplitude of the α1-AR-EPSC and the decay kinetics (τ-decay, p = 0.19, n = 42 pairs). D, There was a significant correlation between the activation and decay kinetics of the α1-AR-EPSC (p = 0.005, n = 43 pairs). Line represents best-fit line by linear regression for visual aid; * denotes statistical significance, and ns denotes not statistically significant.