Table 4.
Relationship between brain activity and GABA+ levels within the MRS VOI
| GABA+task |
GABA+mod |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Brain region | x | y | z | Zmax | p | x | y | z | Zmax | p |
| Negative association between BOLD and GABA+ levels across age groups | ||||||||||
| Unimanual complex | ||||||||||
| S1, S2, IPL | / | −48 | −18 | 27 | 4.00 | 0.011 | ||||
| PMC, M1 | / | −26 | −17 | 68 | 3.55 | 0.013 | ||||
| Bimanual easy | ||||||||||
| S1, S2, IPL | / | −48 | −19 | 27 | 3.9 | 0.028 | ||||
| PMC, M1 | / | −27 | −18 | 65 | 3.52 | 0.034 | ||||
| Bimanual complex | ||||||||||
| S1, S2, IPL | / | −47 | −19 | 28 | 4.58 | 0.010 | ||||
| PMC, M1 | / | −26 | −17 | 68 | 3.65 | 0.028 | ||||
Coordinates are presented in MNI space. S1: primary somatosensory cortex; S2: secondary somatosensory cortex; M1: primary motor cortex; PMC: premotor cortex; IPL: inferior parietal lobule.