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. 2022 Feb 4;15:761–773. doi: 10.2147/JIR.S350421

Table 3.

Functional Modules and Hub Genes Identified from 28 Interconnected Genes

Module 1 (8 Genes)
 *CCL2 C-C motif chemokine ligand 2
 CD163 Cluster of Differentiation 163
 ADORA3 Adenosine A3 Receptor
 P2RY1 Purinergic Receptor P2Y1
 CLEC4E C-Type Lectin Domain Family 4 Member E
 IL1R2 Interleukin 1 Receptor Type 2
 IL1RAP Interleukin 1 Receptor Accessory Protein
 ECHDC3 Enoyl-CoA Hydratase Domain Containing 3
Module 2 (4 Genes)
 *LPL Lipoprotein lipase
 *PDK4 Pyruvate dehydrogenase kinase 4
 ACSL1 Acyl-CoA Synthetase Long Chain Family Member 1
 PLIN2 Perilipin 2
Module 3 (3 Genes)
 *FOXO3 Forkhead box O3
 SESN1 Sestrin 1
 SCO2 Supercritical Carbon Dioxide
Module 4 (7 Genes)
 *EGR1 Early Growth Response 1
 IER2 Immediate Early Response 2
 BTG2 B-cell translocation gene 2
 NR4A1 Nuclear Receptor Subfamily 4 Group A Member 1
 CDK5R1 Cyclin Dependent Kinase 5 Regulatory Subunit 1
 ETS2 ETS Proto-Oncogene 2, Transcription Factor
 PHC2 Polyhomeotic Homolog 2
 KLF7 Krueppel-like factor 7
 NFIA Nuclear factor 1 A-type
 SLC1A3 Excitatory amino acid transporter 1
Module 5 (3 Genes)
 *DUSP5 Dual Specificity Phosphatase 5
 MAP3K8 Mitogen-Activated Protein Kinase Kinase Kinase 8
 SPYR1 Mycobacterium sp. Spyr1

Note: *Hub gene.