Fig 4.

CP-25 synergistically enhances the antiproliferative effect of 5-Fu in HCC cells. a-d: Cell viability was measured by CCK-8 assay at 24h and 48 h after 5-Fu treatment in Hep-G2 and Bel-7402 cells. e, f: Cell viability was measured by CCK-8 assay at 48 h after 5-Fu and/or CP-25 treatment in HepG2 and Bel-7402 cells. g-i: The percentage of apoptosis of Hep-G2 and Bel-7402 cells after 5-Fu and/or OMT treatment tested by FLS. All data are expressed as means ± standard deviation. ^#P< 0.05,^##P< 0.01, versus normal group; ^*P< 0.05, ^**P< 0.01, versus DEN-treated group, ^sP< 0.05, ^ssP< 0.01, versus CP-25 alone group; ^&P< 0.05, ^&&P< 0.01, versus normal group versus 5-Fu alone group.