CP-25 synergistically enhances the invasion and metastasis abilities of 5-Fu in HCC cells. a: Cell invasion ability was measured by scratch assay at 0-24 h after CP-25 and 5-FU alone or in combination treatment in Bel-7402 cells. b-e: Cell invasion and metastasis abilities were measured by transwell assay at 24 h after CP-25 and 5-FU alone or in combination treatment in Bel-7402 cells. All data are expressed as means ± standard deviation. #P< 0.05,##P< 0.01, versus normal group; *P< 0.05, **P< 0.01, versus DEN-treated group, sP< 0.05, ssP< 0.01, versus CP-25 alone group; &P< 0.05, &&P< 0.01, versus normal group versus 5-Fu alone group.