Fig 7.

Effects of CP-25 and 5-FU alone or in combination on the protein expressions of P53, Caspase-9, Cytochrome-C, Bcl-2, Bax, MMP-2 and MMP-9 HCC cells by Western blotting analysis. a-f: The expression level of P53, Caspase-9, Cytochrome-C, Bcl-2, Bax in HepG2 and Bel-7402 at 48 h after CP-25 and 5-FU alone or in combination treatment. g, h: The expression level of MMP-2 and MMP-9 in Bel-7402 at 24 h after CP-25 and 5-FU alone or in combination treatment.All data are expressed as means ± standard deviation. ^#P< 0.05,^##P< 0.01, versus normal group; ^*P< 0.05, ^**P< 0.01, versus DEN-treated group, ^sP< 0.05, ^ssP< 0.01, versus CP-25 alone group; ^&P< 0.05, ^&&P< 0.01, versus normal group versus 5-Fu alone group.