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. 2022 Jan 1;13(3):906–917. doi: 10.7150/jca.66404

Figure 5.

Figure 5

FAM110A promotes tumorigenesis in PDAC by regulating HIST1H2BK. A, B, C and D, HIST1H2BK knockdown abolished the promotion of cell proliferation (D), colony formation capacity (C), migration (A) and invasion (B) caused by overexpression of FAM110A in PANC-1 cells. E, The mRNA levels of EHMT2, POU5F1, DDR1, TNXB, TNF, HSPA1L, STK19, TCF19, and CLIC1 in HIST1H2BK-overexpressing PANC-1 cells using qPCR. Data are shown as the mean ± SD. n = 3 *P < 0.05, **P < 0.01 and *** P < 0.001 were considered significant.