The miR-552-5p is upregulated in exosomes derived from GC plasma and cells. A. Relative expression levels of miR-552-5p in the plasma from GC patients (n=30) and healthy volunteers (n=15), analyzed by qRT-PCR. B. Relative levels of miR-552-5p in plasma exosomes from GC patients (n=30) and healthy volunteers (n=15), as analyzed by qRT-PCR. C. Representative electron micrographs of exosomes isolated from the medium of cultures of SGC-7901, BGC-823 and GES-1 cells. Scale bar, 100 nm. D. Western blotting analysis of the levels of exosome markers (TSG101, Alix and CD9). E. Relative expression of Exo-miR-552-5p in GES-1, SGC-7901 and AGS cells. *p < 0.05; **p < 0.01; ***p < 0.001.