Table 1.
Small-pool PCR quantification after 30 days of treatment with ABA or DMSO
| Cell line | Targeting* | Contractions | Expansions | Alleles | P-value − vs + ** |
|---|---|---|---|---|---|
| 91B-Y | − | 61 (9.5%) | 15 (2.3%) | 642 | 0.53 |
| + | 53 (11.5%) | 12 (2.6%) | 461 | ||
| 89B-Y-DNMT1 | − | 93 (19.2%) | 49 (10.1%) | 483 | 0.78 |
| + | 66 (21.2%) | 30 (9.7%) | 310 | ||
| 59B-Y-HDAC5 | − | 0 (0%) | 14 (1.5%) | 922 | 0.39 |
| + | 0 (0%) | 20 (2.1%) | 942 |
*: –: DMSO only, +: ABA treated.
* *: χ2 test with df = 2 (contractions, expansions, and stable) between − and + targeting within a cell line. For 59B-Y-HDAC5, we used a Fisher’s exact test.