Fig. 4.

Osseous tissue in direct neighborhood to the induced membrane. Values are given as percentage of total defect area and presented as boxplot. a Significantly increased callus tissue when small granules are used compared to large granules and syngenic bone. Exemplary HE-stained slides of defects treated with syngenic bone, small, medium and large granules and b Pink stained areas indicate newly built callus, which is found increased around the induced membrane in groups with small granules. Syn. B syngenic bone; small small granules; medium medium granules; large large granules. a syngenic bone; b small granules; c medium granules; d large granules. dh drill hole; sb syngenic bone; st soft tissue; bm bone marrow; cor corticalis; sca scaffold; nc new callus