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. 2021 Nov 30;40(4):1159–1176. doi: 10.1007/s10555-021-10005-3

Fig. 4.

Fig. 4

Analysis of literature related to acidity and cancer. A Comparison between the extracellular pH reported within solid tumours (red) and pHe values selected for in vitro studies (blue). B Time under acidic conditions in studies using cultured cancer cell lines. The primary literature referred to these as long or short exposure, as indicated by empty and filled circles, respectively. References used in these analyses are listed in Tables 1 and 2