Genetic alteration and clustering analysis of the m6A regulators in patients with PDAC. (A) Waterfall plot of m6A regulators mutation gene and mutation type; (B) hierarchical clustering of m6A regulators, comparing PDAC and adjacent normal tissue; (C) boxplot of m6A regulators, comparing PDAC and adjacent normal tissue. *, P<0.05; ***, P<0.001; ****, P<0.0001. ns represents no statistical significance. PDAC, pancreatic ductal adenocarcinoma.