Figure 5.

Establishment of prognostic signature of early PDAC based on the m⁶A regulators. (A) Forest plots of these 19 m⁶A regulators in TCGA-PDAC cohort; (B) cross-validation for selecting the tuning parameters for the LASSO model. The vertical lines were drawn based on the optimal data according to the minimum criteria and 1-standard error criterion; (C) the path of the coefficients of the 5 m⁶A regulators included in the optimal model; (D) the overall survival curves of the high-risk group and low-risk group in TCGA-PDAC cohort. TCGA, The Cancer Genome Atlas; PDAC, pancreatic ductal adenocarcinoma; LASSO, least absolute shrinkage and selection operator.