Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan;10(1):23. doi: 10.21037/atm-21-6539

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

CXTB attenuates cartilage injury by downregulating the lncRNA HOTAIR. (A) The expression of lncRNA HOTAIR. (B-G) HE staining of the articular cartilage tissue (×200) and the OARSI scores rats in different treatment groups. (H-L) The protein and mRNA expression of MMP13 and TIMP1. *P<0.05; ^#P>0.05. CXTB, cangxitongbi; lncRNA, long non-coding RNA; HOTAIR, Hox transcript antisense intergenic RNA; HE, hematoxylin and eosin; OARSI, Osteoarthritis Research Society International; MMP13, matrix metallopeptidase 13; TIMP1, tissue inhibitor matrix metalloproteinase 1; NC, negative control; AAV, adeno-associated virus.