Table 1. Baseline characteristics and echocardiographic measurements of the study patients.
| Parameters | Early-generation CoreValve (N=15) | Newer-generation valves (N=10) | P value |
|---|---|---|---|
| Age (year) | 72.0±17.2 | 72.8±11.7 | 0.76 |
| Male, n [%] | 11 [73] | 7 [70] | >0.99 |
| Height (cm) | 165.1±9.0 | 166.7±9.7 | 0.52 |
| Weight (kg) | 64.3±14.6 | 57.8±15.0 | 0.26 |
| Body mass index (kg/m2) | 23.5±4.1 | 20.8±4.5 | 0.15 |
| Systemic hypertension, n [%] | 9 [60] | 9 [90] | 0.18 |
| Diabetes mellitus, n [%] | 3 [20] | 1 [10] | 0.63 |
| Chronic obstructive lung disease, n [%] | 3 [20] | 3 [30] | 0.65 |
| Coronary artery disease, n [%] | 7 [47] | 1 [10] | 0.09 |
| Prior myocardial infarction, n [%] | 1 [7] | 0 | >0.99 |
| Prior percutaneous coronary intervention, n [%] | 2 [13] | 1 [10] | >0.99 |
| Heart failure, NYHA functional class III/IV, n [%] | 12 [80] | 6 [60] | 0.38 |
| Prior cerebrovascular accident, n [%] | 5 [33] | 2 [20] | 0.66 |
| Previous atrial fibrillation, n [%] | 5 [33] | 3 [30] | >0.99 |
| Peripheral arterial occlusion disease, n [%] | 1 [7] | 1 [10] | >0.99 |
| Prior permanent pacemaker implantation, n [%] | 4 [27] | 2 [20] | >0.99 |
| STS-PROM score (%) | 7.3±4.9 | 6.2±4.1 | 0.78 |
| Baseline echocardiographic findings | |||
| Left ventricular ejection fraction (%) | 52.2±11.7 | 52.1±13.6 | 0.71 |
| Right ventricular ejection fraction (%) | 54.5±8.1 | 60.8±4.0 | 0.02* |
| Ascending aorta diameter (mm) | 38.7±4.9 | 38.1±7.0 | 0.66 |
| ≥moderate mitral regurgitation, n [%] | 13 [87] | 4 [40] | 0.03* |
| Right ventricular systolic pressure (mmHg) | 47.1±10.7 | 39.6±9.0 | 0.11 |
Continuous variables are expressed as mean ± standard deviation. *, significance level, P<0.05. NYHA, New York Heart Association; STS-PROM, Society for Thoracic Surgery-probability of mortality score.