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. 2022 Jan;10(1):9. doi: 10.21037/atm-21-5583

Figure 4.

Figure 4

The distribution of MPO content in the inferior vena cava over time after inferior vena cava thrombosis. (A) Western blot analysis of MPO expression at different time points after venous thrombosis (1, 3, and 7 days). MPO was higher in the IVCL-1D and IVCL-3D groups, but significantly lower in the IVCL-7D group. Expression of the exosomal markers CD63 and Alix increased after venous thrombosis. (B) Immunofluorescence analysis of the distribution of MPO in the inferior vena cava at different time points after thrombosis. MPO was mainly distributed in the blood vessel wall in the IVCL-1D group and in the emboli in the IVCL-3D group, while it had almost disappeared in the IVCL-7D group (×50 µm). *, P<0.05. DAPI, 4’,6-diamidino-2-phenylindole; MPO, myeloperoxidase.