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Exosomes loaded with RBP-J decoy oligodeoxynucleotides (ODNs) ameliorated liver fibrosis induced by CCl4 in mice. Liver sections were subjected to Sirius red (A) and Masson staining (B). Liver sections were subjected to immunohistochemical staining for Col1α1 (C) and αSMA (D). (E) Areas positive for Sirius red staining in (A), Masson staining in (B), Col1α1 in (C), and αSMA in (D) were quantitatively compared. Bars = means ± SD; * P < 0.05, ** P < 0.01.
