Figure 9.
Other strategies for tumor-derived extracellular vesicles in cancer therapy. A) Outline of endogenous nanosonosensitizers for centered US-expanded focusing on conveyance to perceive homotypic malignant growth cells, boosts responsive medication discharge, and improved SDT. B) In vivo homotypic targeting potential of EXO-DVDMS derived from 4T1 tumor cells. Includes in vivo images, quantification, ex vivo images, and quantitative analysis of fluorescence intensity. Adapted with permission from 138. Copyright Year 2019, IVYSPRING. C) Schematics of nanoparticle-intervened metabolic marking of azide groups on the perivascular tumor cell film and intercellular exchange of the azide gatherings to profound cancer cells through EVs for upgraded cancer focusing on and infiltration of DBCO-Ce6 by a bioorthogonal click reaction. D) Confocal pictures of frozen areas of tumors that were extracted from mice after treatment with DBCO-Ce6, Ac4ManNAz/DBCO-Ce6, or Az-NPs/DBCO-Ce6. Adapted with permission from 197. Copyright Year 2020, Elsevier.