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Accumulation of magnetic nanoparticles within cells. (A) and (B) Diagrams depicting intracellular uptake of magnetic nanoparticles by phagocytic cells. The size of the endosomes can be as large as 5 µm. TEM images of unlabeled (C) and SPION-labeled macrophages (D). Red arrows indicate the endocytosed aggregates of SPIONs within endosomes. Reproduced with permission from 106. Copyright 2011, IOP Publishing.
