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. 2022 Jan 24;12(4):1769–1782. doi: 10.7150/thno.68456

Figure 6.

Figure 6

Treatment efficacy of SHIFT&DOX in a rat orthotopic HCC model. (A) Schematic of the evaluation process. (B) Representative MRI images. (C) Representative resected tumor lesions for 14 days. (D) Histological staining of representative resected tumor lesions for 14 days. (E) Quantitative analysis of relative tumor volume. (F) Quantitative analysis of Ki-67 positive rate for 14 days in tumors. (G) Tissue and organ safety evaluation. Data represent mean ± SD, n = 3. * p < 0.05; ** p < 0.01; *** p < 0.001, **** p < 0.0001, one-way ANOVA test.